We would like to invite you to our second COMPARE Team Science seminar of the year at the University of Birmingham on  Friday 5th July at 14:00.

The seminar will feature Ngoc Vo Thi (Kate), third year PhD student from Professor Chris Denning’s lab at the University of Nottingham. The Denning group’s research interests are in cardiomyocyte differentiation of human embryonic and induced stem cells for use in drug screening, and in production of new in vitro models of genetic-based cardiovascular diseases. Kate uses different CRISPR/Cas9-edited stem cell lines in B2-Adrenergic receptor (ADRB2) and GRK5 that had been established in the lab to study the cardioprotective functions of GRK5-L41 single nucleotide polymorphism and the underlying mechanism.

Kate's presentation is entitled "Using footprint-free CRISPR/Cas9-edited human pluripotent stem cells to study GRK5-L41 mediated cardioprotection during catecholamine stress"